Postdoctoral Researcher · University Hospital Bonn

Dillon Corvino, PhD

T cell & NK cell biology  ·  Immuno-oncology  ·  Single-cell multi-omics

Immunologist with 6+ years of postdoctoral experience across tumour immunology, viral immunity, and translational immuno-oncology. I combine wet-lab expertise in human primary tissue and genetic engineering with independent end-to-end single-cell and spatial multi-omics analysis.

My focus is understanding cytotoxic lymphocyte biology and advancing cell therapy strategies from discovery through publication.

Open to industry roles in immuno-oncology and cell therapy across the EU and Australia

Dillon Corvino
970
Citations
15
h-index
6+
Yrs postdoc
€110k
Funding (PI)
01

Research

Cytotoxic lymphocyte biology

NK cell plasticity and dysfunction in the tumour microenvironment.

CD8 T cell states Type I IFN dysfunction Unconventional T cells Anti-tumour & anti-viral

Single-cell & spatial multi-omics

Independent end-to-end analysis pipelines, run on HPC.

scRNA-seq CITE-seq scATAC-seq scTCR-seq Spatial transcriptomics High-multiplex imaging

Cell engineering & therapy

Genetic engineering of primary human lymphocytes.

CRISPR KO / KI / OE Primary NK & CD8 T cells CAR-NK CAR-T Preclinical models

Translational immunology

Reverse-translational discovery — bench to publication.

Clinical immune phenotyping Biomarker development Patient tissue Computational analysis

Core expertise

Wet Lab
Spectral/Conventional flow cytometry · 40+ colours CRISPR/Cas9 · primary immune cells Primary human tissue & ex vivo models Preclinical murine models
CAR-NK & CAR-T engineering FACS sorting & high-dim panel design Lentiviral / adenoviral overexpression Murine tumour models LCMV acute & chronic infection Organoids · ALI · tissue-fragment cultures CAM (in ovo) assays Functional assays — cytotoxicity, ICS, degranulation
Computational
scRNA-seq · CITE-seq · scATAC-seq · scTCR-seq R / tidyverse HPC execution
Spatial transcriptomics & imaging Bulk RNA · TCR · DNA-seq & WES Next-Gen sequence alignment Whole-genome CRISPR screen Pseudotime & trajectory inference Nextflow · Snakemake · SLURM Conda / Mamba Integration & batch correction GRN & cell–cell communication TCR repertoire analysis Applied ML & TCR embedding Scientific viz · Illustrator
Leadership
PI — €100k BMBF GO-Bio grant Independent programme ownership Hiring lead · 3 PhDs & 2 technicians
Established 3 institute-wide platforms (flow, multi-omics, organoids) Mentorship of 10+ PhD / MSc / BSc students International collaboration across 4 continents 20+ publications Peer reviewer · Nat Comms, Immunity, Cancer Immunol Res Scientific consultant · Axelia Oncology Inventor · provisional patent (immunocompetence biomarkers)
02

Publications

Full list on Google Scholar  ·  ORCID 0000-0003-0683-1369  ·  970 citations  ·  h-index 15

2025 2024

Giordano FA, Layer JP, … Corvino D, et al.

L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial

Nature Communications, 2024

DOI ↗

Hosni S, Kilian V, Klümper N, … Corvino D, et al.

Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma

Cancer Research, 2024

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Casey M, Lee C, Kwok WY, … Corvino D, et al.

Regulatory T cells hamper the efficacy of T-cell-engaging bispecific antibody therapy

Haematologica, 2024

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2023

Corvino D, Rommel D, Schneppenheim F, Bald T

Stressed out: NKp46 binds ecto-calreticulin

Immunology and Cell Biology, 2023

DOI ↗

Wang Y, De Labastida Rivera F, … Corvino D, et al.

STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

Journal of Clinical Investigation, 2023

DOI ↗
2022

Corvino D, Kumar A, Bald T

Plasticity of NK cells in Cancer

Frontiers in Immunology, 2022

DOI ↗

Li X-Y, Corvino D, Nowlan B, et al.

NKG7 Is Required for Optimal Antitumor T-cell Immunity

Cancer Immunology Research, 2022

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2020

Braun M, … Corvino D, … Bald T

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells

Immunity, 2020

DOI ↗

Ng SS, … Corvino D, … Engwerda CR

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Nature Immunology, 2020

DOI ↗
2019

Smith C, Corvino D, Beagley L, et al.

T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response

Journal of Clinical Investigation, 2019

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03

Contact

Open to discussing collaborations, translational research opportunities, and industry roles in immuno-oncology, cell therapy, and computational biology — across the EU and Australia.

Email dilloncorvino@me.com Copied
Location Bonn, Germany · EU work authorisation
Institution University Hospital Bonn — Abdullah Lab