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Postdoctoral Researcher · University Hospital Bonn

Dillon Corvino, PhD

T cell & NK cell biology  ·  Immuno-oncology  ·  Single-cell multi-omics

Immunologist with 6+ years of postdoctoral experience across tumour immunology, viral immunity, and translational immuno-oncology. I combine wet-lab expertise in human primary tissue and genetic engineering with independent end-to-end single-cell and spatial multi-omics analysis.

My focus is understanding cytotoxic lymphocyte biology and advancing cell therapy strategies from discovery through publication.

Open to Scientist / Senior Scientist roles in cell therapy and computational immunology across the EU and Australia

Dillon Corvino
970
Citations
15
h-index
20+
Publications
€110k
Funding (PI)
01

Experience

  1. Jun 2025 – present

    Postdoctoral Researcher

    University Hospital Bonn · Abdullah Lab

    Leading an independent programme on unconventional T cell state transitions and tissue-resident immunity in antiviral and chronic disease (LCMV, liver fibrosis). Hiring lead for 3 PhD students and 2 technicians.

  2. 2024

    Our daughter was born

    Our family grew.

  3. Jun 2023 – present

    Scientific Consultant

    Axelia Oncology · Melbourne, Australia

    Immunological data analysis and interpretation for a clinical-stage innate immunotherapy programme in solid tumours. The industry side of the same questions.

  4. Mar 2020 – Jun 2025

    Postdoctoral Researcher

    University Hospital Bonn · Bald Lab · Bonn, Germany

    Owned the NK cell cancer immunotherapy programme. Ran single-cell and spatial multi-omics analyses end to end, engineered primary human NK and CD8 T cells, and secured the BMBF GO-Bio grant as sole PI.

  5. Mar 2020

    Moved from Brisbane to Bonn

    New country, new lab, new language. Australia to Germany, and the start of the NK cell immunotherapy programme.

  6. Sep 2019 – Feb 2020

    Postdoctoral Researcher

    QIMR Berghofer · Brisbane, Australia

    Single-cell profiling of tumour-infiltrating NK and CD8 T cells in head and neck squamous cell carcinoma.

  7. 2015 – 2019

    PhD, Immunology

    QIMR Berghofer / University of Queensland · Supervisor Prof. Rajiv Khanna

    Thesis: strategies for improving adoptive T-cell immunotherapy.

  8. 2011 – 2014

    BBiomedSci, Honours Class I

    Griffith University · Australia

    Where the lab work started.

02

Core expertise

Immunology
NK cell plasticity & dysfunction in tumours CD8 T cell states · Type I IFN dysfunction Unconventional & tissue-resident T cells
Anti-tumour & anti-viral immunity Translational & reverse-translational discovery Clinical immune phenotyping · patient tissue Biomarker development
Wet Lab
Spectral/Conventional flow cytometry · 40+ colours CRISPR/Cas9 · primary immune cells Primary human tissue & ex vivo models Preclinical murine models
CAR-NK & CAR-T engineering FACS sorting & panel design Lentiviral / adenoviral overexpression Syngeneic tumour & LCMV infection models Organoids · ALI · tissue fragments · CAM assays Functional assays — cytotoxicity, ICS, degranulation
Computational
scRNA-seq · CITE-seq · scATAC-seq · scTCR-seq R / tidyverse · ggplot2 · Quarto HPC execution
Spatial transcriptomics & imaging Bulk RNA · TCR · WES CellRanger · STARsolo · Salmon Harmony integration · pseudobulk DE Trajectory & RNA velocity · SCENIC Cell–cell communication · CellChat · NicheNet TCR repertoire · scRepertoire · immunarch Nextflow · Snakemake · SLURM · Apptainer Python · applied ML
Leadership
PI — €100k BMBF GO-Bio grant Independent programme ownership Hiring lead · 3 PhDs & 2 technicians
Established 3 institute-wide platforms (flow, multi-omics, organoids) Mentorship of 10+ PhD / MSc / BSc students International collaboration across 4 continents Peer reviewer · Nat Comms, Immunity, Cancer Immunol Res Scientific consultant · Axelia Oncology Inventor · provisional patent (immunocompetence biomarkers)
04

Publications

Full list on Google Scholar  ·  ORCID 0000-0003-0683-1369  ·  970 citations  ·  h-index 15

2025 2024

Giordano FA, Layer JP, … Corvino D, et al.

L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial

Nature Communications, 2024

Why it matters Phase I/II evidence for adding CXCL12 inhibition to radiotherapy in newly diagnosed glioblastoma.

DOI ↗

Hosni S, Kilian V, Klümper N, … Corvino D, et al.

Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma

Cancer Research, 2024

DOI ↗

Casey M, Lee C, Kwok WY, … Corvino D, et al.

Regulatory T cells hamper the efficacy of T-cell-engaging bispecific antibody therapy

Haematologica, 2024

Why it matters Regulatory T cells limit the efficacy of T-cell-engaging bispecific antibodies, a factor for therapy design.

DOI ↗
2023

Corvino D, Rommel D, Schneppenheim F, Bald T

Stressed out: NKp46 binds ecto-calreticulin

Immunology and Cell Biology, 2023

DOI ↗

Wang Y, De Labastida Rivera F, … Corvino D, et al.

STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

Journal of Clinical Investigation, 2023

DOI ↗
2022

Corvino D, Kumar A, Bald T

Plasticity of NK cells in Cancer

Frontiers in Immunology, 2022

DOI ↗

Li X-Y, Corvino D, Nowlan B, et al.

NKG7 Is Required for Optimal Antitumor T-cell Immunity

Cancer Immunology Research, 2022

DOI ↗
2020

Braun M, … Corvino D, … Bald T

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells

Immunity, 2020

Why it matters CD226 degradation as an immunotherapy resistance mechanism, informing co-stimulatory target selection and combinations.

DOI ↗

Ng SS, … Corvino D, … Engwerda CR

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Nature Immunology, 2020

Why it matters Defines an effector pathway with direct relevance to cell therapy potency and target biology.

DOI ↗
2019

Smith C, Corvino D, Beagley L, et al.

T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response

Journal of Clinical Investigation, 2019

Why it matters Supports TCR-seq-based monitoring and patient selection for adoptive T cell therapy.

DOI ↗

See all publications on Google Scholar →

05

Contact

Open to Scientist and Senior Scientist roles in cell therapy and computational immunology across the EU and Australia, and to collaborations and translational research opportunities.

Email dilloncorvino@me.com Copied
Location Bonn, Germany · EU work authorisation
Institution University Hospital Bonn — Abdullah Lab